Current practices in epilepsy monitoring units (EMU) in India.

AIM: As an initial step to develop guidelines for epilepsy monitoring units (EMUs) appropriate for developing countries, we inquired the existing practices in EMUs in India. METHODS: After checking for the content and face validity as well for clarity, we sent a 52-item online non-anonymized questionnaire to all the 52 EMUs in India. RESULTS: The questionnaire was completed by 51 of the 52 EMUs (98% response rate). The majority of the EMUs are located in major cities and 51% are located in non-governmental corporate hospitals. There are total of 122 prolonged video-EEG monitoring (PVEM) beds in India and 70% EMUs have ≤2 beds. Approximately two-thirds of the EMUs have defined protocols for pre-procedure consent and risk assessment, management of seizure clusters and status epilepticus, continuous observation of patients, and peri­ictal testing. Only one-third of the EMUs have protocols for management of post-ictal psychosis, anti-suffocation pillows, and protected environment within bathrooms. The waiting period for PVEM is more (49.9 ± 101 vs. 4.9 ± 10.9 days; p = 0.04) and mean cost for 3-day PVEM is less (INR 8311 ± 9021 vs. 30,371 ± 17,563; p <0.0001) in public as compared to private hospitals. There was a negative correlation between cost of PVEM and the waiting period (r=-0.386; p = 0.01). Safety practices are similar in public and private hospitals. CONCLUSIONS: Although practices in EMUs in India vary widely, they are comparable to those in developed countries. India has severe shortage of EMUs and long waiting lists for affordable PVEM.

Impact of COVID-19 pandemic on epilepsy practice in India: A tripartite survey.

OBJECTIVE: To assess the impact of ongoing COVID-19 pandemic on epilepsy care in India. METHODS: We conducted a three-part survey comprising neurologists, people with epilepsy (PWE), and 11 specialized epilepsy centers across India. We sent two separate online survey questionnaires to Indian neurologists and PWE to assess the epilepsy practice, seizures control, and access to care during the COVID-19 pandemic. We collected and compared the data concerning the number of PWE cared for and epilepsy procedures performed during the 6 months periods preceding and following COVID-19 lockdown from epilepsy centers. RESULTS: The survey was completed by 453 neurologists and 325 PWE. One third of the neurologist reported >50 % decline in outdoor visits by PWE and EEG recordings. The cumulative data from 11 centers showed 65-70 % decline in the number of outdoor patients, video-EEG monitoring, and epilepsy surgery. Working in a hospital admitting COVID-19 patients and use of teleconsultation correlated with this decline. Half of PWE had postponed their planned outpatient visits and EEG. Less than 10 % of PWE missed their antiseizure medicines (ASM) or had seizures due to the nonavailability of ASM. Seizure control remained unchanged or improved in 92 % PWE. Half of the neurologists started using teleconsultation during the pandemic. Only 4% of PWE were afflicted with COVID-19 infection. CONCLUSIONS: Despite significant decline in the number of PWE visiting hospitals, their seizure control and access to ASMs were not affected during the COVID-19 pandemic in India. Risk of COVID-19 infection in PWE is similar to general population.

Factors affecting foot posture in young adults: a cross sectional study.

OBJECTIVE: Age, Body Mass Index (BMI) and flexibility are factors affecting foot posture, which is poorly understood in young adults. The objective of this study is to discover the relationships among these factors. METHODS: 252 healthy participants (106 males, 146 females) between the ages of 18 and 25 were selected. BMI and the Foot Posture Index - 6 item version (FPI-6) were assessed, a Beighton score was obtained for each participant, and a lunge test was conducted. RESULTS: Pronated feet (indicated by an FPI-6 score of 6+ (had a weak positive correlation with Beighton score (r=0.25, p= 0.05, 95% CI [0.01 to 0.47]) and a weak negative correlation with BMI (r=0.31, p = 0.01, 95% CI [-0.52 to -0.07]). Females had a higher prevalence of pronated feet (81.75%) than males (18.75%). CONCLUSION: There is a mild relationship between ligament laxity and foot pronation, and females are more prone to have pronated feet than males. No correlation was found between body weight and pronated feet.

Physical therapists' perspectives on improving walking capacity in patients with stroke: a cross-sectional study from Saudi Arabia.

OBJECTIVES: Stroke is a serious condition that leads to disability and death, which affects around 16 million people worldwide each year. The considerable loss of function after stroke is likely to impede walking ability. The current study was to understand the practices of physical therapists in Saudi Arabia and their perspectives on treatment to improve walking capacity after stroke. METHODS: This prospective cross-sectional survey was conducted using a 12-item, semistructured questionnaire, which included demographic characteristics and physical therapy practices. The questionnaires were distributed as hard copies to physical therapists working in Saudi Arabia and were asked to return the forms after completion. Totally 191 respondents from 18 institutions in Saudi Arabia completed the survey and were included in the analysis. RESULTS: There was comparable agreement from respondents regarding the use of ankle foot orthosis (84.8%). The use of walking aids was supported more by physical therapists with higher qualifications (post-graduates=40%, doctorates=55.6%), while evidence-based practice showed a higher rate in less-experienced to moderately experienced physical therapists (2-5 years=24.2%, 5-10 years=19.3%). CONCLUSION: Variable responses from different sectors according to qualification, experience, and institution were observed among the physical therapists in Saudi Arabia for improving the walking capacity in patients after Stroke.

Can transcranial magnetic stimulation be used to evaluate patients with narcolepsy?

Narcolepsy is a rare, chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy and other manifestations of dissociated rapid eye movement in sleep. We assessed the utility of transcranial magnetic stimulation (TMS) as an objective tool to elucidate the cortical excitability changes and also to analyze its role in assessing the treatment efficacy in narcolepsy. Eight patients with narcolepsy under our regular follow-up from 2000 to 2009 at our Sleep disorder clinic were chosen. All of them underwent polysomnography, multiple sleep latency tests and TMS. Resting motor threshold (RMT), cortical silent period (CSP) and central motor conduction time (CMCT) were assessed using TMS in both drug-naïve and post-treatment states. Eight controls were also subjected to all the three investigations. Appropriate statistical methods were used. The mean RMT (%) pre-treatment was higher in narcolepsy patients than that in controls, and it normalized following treatment. CSP and CMCT were unaffected in narcolepsy patients as compared to controls. This study shows that the cortical excitability is significantly low in narcolepsy patients. This motor cortex hypoexcitability becomes normal with the institution of treatment, pari passu with the control of symptoms. In future, TMS may be considered as an effective tool for documenting the treatment efficacy in patients with narcolepsy.